THE 10th Sugiyama Laboratory Open Symposium
“ Role of DMPK scientists in bringing precision medicine into real-world“
Date:Oct 20 13:50－17:50, 2017
Place: RIKEN Yokohama Main Building Hall
Language：English
Registration Fee: Symposium Free, banquet 3,000yen
Registration ; mail to yslab.secretary [at] ml.riken.jp with below information.
name/affiliation/mail address/banquet(attend or not)
This Symposium is a part of the RIKEN Symposium Series.
Program
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13:50-14:00
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Opening remarks Yuichi Sugiyama (Sugiyama Laboratory, RIKEN Innovation Center) |
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14:00-14:30
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Systems-based understandings of drug toxicities Masashi Honma (The University of Tokyo Hospital) |
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14:30-15:00
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Current Approaches for Evaluating OATP Family Transporters in Drug Discovery Saki Izumi (Eisai Co., Ltd.) |
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15:00-15:30
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Complex DDI of telaprevir and maraviroc Emi Kimoto (Pfizer Inc.) |
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15:30-15:50 |
Coffee break |
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15:50-16:20
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Physiologically based pharmacokinetic (PBPK) modeling approach of cerivastatin to quantitatively describe drug-drug interactions associated with hepatic uptake transporter and
metabolic enzymes Yoshiaki Yao (Astellas Pharma Inc.) |
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16:20-16:50
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Kinetic consideration of OATP contribution to drug disposition based on extended clearance concept: Insight to genetic and ethnic variability and drug-drug
interaction Yoshiko Tomita (Sumitomo Dainippon Pharma Co., Ltd.) |
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16:50-17:20
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Bilirubin and its conjugates levels in the blood circulation can be a bio-marker for drug-drug interaction?: Various drug transporters/drug-metabolism enzymes are involved in
bilirubin homeostasis Seiji Miyauchi (Toho university) |
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17:20-17:50 |
General Discussion Yuichi Sugiyama (Sugiyama Laboratory, RIKEN Innovation Center) |
| 18:00-19:45 |
Banquet (Cafeteria at Yokohama RIKEN) |
Contact to：Sugiyama's Laboratory
Email: yslab.secretary [at] ml.riken.jp
HP: http://www.sugiyamalab.com/
Tel: 045‐503‐9210